MT1 research peptide
What is Melanotan I?
Melanotan I (MT1) is a synthetic 13-residue analog of α-melanocyte-stimulating hormone (α-MSH), also written [Nle4, D-Phe7]-α-MSH or NDP-α-MSH. It keeps the full linear α-MSH sequence, acetylated at the N-terminus and amidated at the C-terminus, with two substitutions: norleucine replaces methionine at position 4, removing the oxidation-prone sulfur, and D-phenylalanine replaces L-phenylalanine at position 7, which makes the core of the molecule more resistant to enzymes and increases its affinity for the melanocortin 1 receptor (MC1R).
MT1 Labs supplies Melanotan I as a lyophilized powder in 10 mg vials. Each lot is tested by ILS Laboratories for HPLC purity, identity against a reference standard and net content, with a fentanyl screen, and the certificate is published here before sale through Klow.bio.
MT1 is a linear peptide and a different compound from Melanotan II (MT2), which is a shorter, cyclic analog. The two have different formulas and molecular weights (1646.85 vs 1024.18 g/mol).
Structural features that matter for analysis
MT1 is linear, with an acetylated N-terminus (Ac-Ser1) and amidated C-terminus (Val13-NH2). Position 4 is norleucine (Nle) and position 7 is D-phenylalanine. The central His-D-Phe-Arg-Trp segment is the core shared by melanocortin receptor ligands. The single tryptophan (Trp9) is its most oxidation-sensitive residue.
Sizes and ordering
Melanotan I is supplied as a lyophilized powder in 10 mg vials. It is sold through klow.bio, operated by Klow Labs LLC, where current pricing, bundle discounts and shipping options are listed. Orders ship the next business day. Same-day cutoff is 4:00 PM CT, with overnight and 2-day options at checkout.